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In addition, the indole core is substituted at R3 which has a carbonyl team that is also bonded to some napthalene moeity. Napthalene is a bicyclic framework of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it as being a ketone. JWH-018 is an analog of THJ-018, in which the Main indazole framework is substituted using an indol